The acura TL's have a great reputation for being great cars. Acuras and Hondas in general are some of the best as far as a good strong running vehicle. I havent dove into the 2012's yet (or any 2012's for that matter) but thats a good choice. Id recommend a acura to anyone.
Heres the thread I made that tells all what Im about and shit. But Ill answer your question with a few other questions.
year
make
model
what are the symptoms
but to answer your question. Technically there is NOTHING a spindle has that can make noise. Its the things attatched to it that will make noise.
Optymuss has 1 possibility. a wheel bearing can make noise (only while moving)
you also have ball joints (which will "clunk" while going over bumps)
and Tie rod ends (will make noises while making turns)
some european cars have bushings in the spindle, some have ball joints built in, theres all kinds of things that can cause that.
Tell me what kinda car (year, make & model) and I can prolly narrow it for you and even give you some ball park prices on how to fix it!!